[{"data":1,"prerenderedAt":99},["ShallowReactive",2],{"notizie-en-periodontitis-alzheimers-disease-link":3},{"post":4,"body":31,"related":32},{"slug":5,"title":6,"date":7,"modified":8,"excerpt":9,"minutes":10,"image":11,"service":14,"en":15},"dalla-bocca-al-cervello-ecco-come-la-parodontite-puo-innescare-lalzheimer","Dalla bocca al cervello: ecco come la parodontite può innescare l’Alzheimer","2018-11-20","2021-05-09","Uno studio recentemente pubblicato dalla rivista PLOS ONE ha evidenziato come la parodontite, malattia infiammatoria che distrugge le strutture di supporto dei denti, può accelerare l’insorgenza…",2,{"width":12,"height":13,"alt":6},1200,628,"parodontologia",{"slug":16,"title":17,"description":18,"excerpt":19,"minutes":10,"summary":20,"keywords":24,"imageAlt":30},"periodontitis-alzheimers-disease-link","From Mouth to Brain: How Periodontitis Can Trigger Alzheimer's","A study in PLOS ONE found that gum disease bacteria reached the brain of mice and caused Alzheimer's-like damage. Learn what the research showed.","A study recently published in the journal PLOS ONE has shown that periodontitis, an inflammatory disease that destroys the supporting structures of the teeth, can accelerate the onset of Alzheimer's…",[21,22,23],"In a study published in PLOS ONE, mice given repeated oral doses of periodontal bacteria for 22 weeks developed far more beta-amyloid in their brain tissue.","The exposed mice also showed more brain inflammation and fewer intact neurons, and periodontal bacterial DNA was found in their brain tissue.","The study was the first to show that exposure to periodontal bacteria causes senile plaques that accelerate the cognitive decline typical of Alzheimer's.",[25,26,27,28,29],"periodontitis and Alzheimer's","gum disease and dementia","oral bacteria and the brain","beta-amyloid and gum disease","oral hygiene and cognitive decline","Illustration of the human brain","\u003Cp>\u003Cem>A study recently published in the journal PLOS ONE has shown that periodontitis, an inflammatory disease that destroys the supporting structures of the teeth, can accelerate the onset of Alzheimer's disease.\u003C\u002Fem>\u003C\u002Fp>\n\u003Cp>Understanding the causes and risk factors of Alzheimer's is essential for developing treatments, since it is a sporadic or late-onset disease whose causes and mechanisms are still poorly understood.\u003C\u002Fp>\n\u003Cp>The link between cognitive disorders and oral hygiene has been known for some time. To study the effects of oral bacteria on the brain more closely, Dr Watanabe, a lecturer in periodontics at the \u003Cstrong>University of Illinois at Chicago\u003C\u002Fstrong>, and her colleagues induced chronic periodontitis in a group of laboratory mice. After 22 weeks of repeated oral application of the bacteria, the researchers examined the mice's brain tissue and compared it with that of untreated mice.\u003C\u002Fp>\n\u003Cp>The mice exposed to the bacteria had considerably higher levels of accumulated \u003Cstrong>beta-amyloid\u003C\u002Fstrong>, a senile plaque found in the brain tissue of patients with Alzheimer's. This group also had greater \u003Cstrong>brain inflammation\u003C\u002Fstrong> and \u003Cstrong>fewer intact neurons\u003C\u002Fstrong> as a result of degeneration.\u003C\u002Fp>\n\u003Cp>In addition, \u003Cstrong>DNA from periodontal bacteria\u003C\u002Fstrong> was found in the mice's brain tissue, and a bacterial protein was observed inside their neurons, demonstrating that the bacteria had travelled from the mouth to the brain.\u003C\u002Fp>\n\u003Cp>The results of this study therefore showed that long-term exposure to the bacteria responsible for \u003Cstrong>periodontitis\u003C\u002Fstrong>, a preventable and treatable gum infection, causes inflammation and degeneration of \u003Cstrong>neurons\u003C\u002Fstrong> in mice in a way similar to the effects of \u003Cstrong>Alzheimer's\u003C\u002Fstrong> in humans.\u003C\u002Fp>\n\u003Cp>Other studies had already investigated the association between cognitive disorders and periodontitis, but this is the very first to show that exposure to periodontal bacteria causes the formation of senile plaques that trigger the accelerated cognitive decline typical of Alzheimer's.\u003C\u002Fp>\n\u003Cp>This important finding confirms once again that looking after your oral hygiene is essential not only for the health of your mouth but for your whole body.\u003C\u002Fp>\n\u003Cp>\u003Cem>Source: Vladimir Ilievski, Paulina K. Zuchowska, Stefan J. Green, Peter T. Toth, Michael E. Ragozzino, Khuong Le, Haider W. Aljewari, Neil M. O’Brien-Simpson, Eric C. Reynolds, Keiko Watanabe, \u003Cstrong>Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice\u003C\u002Fstrong>\u003C\u002Fem>\u003C\u002Fp>",[33,55,77],{"slug":34,"title":35,"date":36,"modified":36,"excerpt":37,"minutes":10,"image":38,"service":14,"en":39},"via-il-dente-via-il-ricordo-la-cattiva-salute-orale-puo-compromettere-la-tua-memoria","Via il dente, via il ricordo: la cattiva salute orale può compromettere la tua memoria","2022-09-08","Se vuoi proteggere il tuo cervello non trascurare l’igiene orale: ogni dente perso, infatti, può causare un aumento del’1,4% del rischio di un deterioramento cognitivo e dell’1,1% di sviluppare…",{"width":12,"height":13,"alt":35},{"slug":40,"title":41,"description":42,"excerpt":43,"minutes":10,"summary":44,"keywords":48,"imageAlt":54},"tooth-loss-memory-and-dementia-risk","Tooth Loss, Memory and Dementia: How Oral Health Affects the Brain","Each lost tooth raises the risk of cognitive impairment by 1.4% and dementia by 1.1%, a JAMDA meta-analysis found. Learn how oral health protects memory.","If you want to protect your brain, do not neglect your oral hygiene: each tooth you lose can increase the risk of cognitive impairment by 1.4% and the risk of developing some form of dementia by 1.1%.",[45,46,47],"A JAMDA meta-analysis found that each lost tooth increases the risk of cognitive impairment by 1.4% and the risk of developing dementia by 1.1%.","Adults who had lost more than one tooth were 1.5 times more likely to develop cognitive impairment and 1.3 times more likely to develop dementia.","The risk dropped sharply when missing teeth were replaced with prostheses or dentures, possibly because tooth loss makes chewing difficult and leads to nutritional deficiencies.",[49,50,51,52,53],"tooth loss and dementia","oral health and memory","missing teeth cognitive decline","gum disease and alzheimer’s","dentures and dementia risk","Older adult smiling, illustrating oral health and memory",{"slug":56,"title":57,"date":58,"modified":8,"excerpt":59,"minutes":10,"image":60,"service":14,"en":61},"pubblicato-studio-sulla-correlazione-tra-parodontite-edentulia-e-rischio-di-mortalita","Pubblicato studio sulla correlazione tra parodontite, edentulia e rischio di mortalità","2021-04-14","La parodontite colpisce circa il 50% degli adulti nel mondo. Nella sua forma più grave e nelle sue conseguenze definitive (edentulia) rappresenta la sesta patologia più diffusa, colpendo il 9,8%…",{"width":12,"height":13,"alt":57},{"slug":62,"title":63,"description":64,"excerpt":65,"minutes":10,"summary":66,"keywords":70,"imageAlt":76},"periodontitis-tooth-loss-mortality-risk-study","Periodontitis, Tooth Loss and Mortality Risk: New Study","A 2021 meta-analysis of 57 studies and 5.71 million people links periodontitis and edentulism to a higher risk of death. Key figures and what they mean.","Periodontitis affects around 50% of adults worldwide. In its most severe form and in its final consequences (edentulism, the loss of all teeth), it is the sixth most widespread disease, affecting…",[67,68,69],"Periodontitis affects about 50% of adults worldwide, and in its most severe form and final consequence, edentulism, it is the sixth most common disease, affecting 9.8% of adults.","A 2021 systematic review of 57 studies with 5.71 million participants found periodontitis associated with all-cause mortality with a relative risk of 1.46, rising to 1.64 for edentulism.","The association between periodontitis and all-cause mortality, and between edentulism and cardiovascular mortality, was stronger in people over 65.",[71,72,73,74,75],"periodontitis and mortality","gum disease and risk of death","edentulism mortality risk","periodontitis systemic disease","tooth loss and life expectancy","Researcher reviewing scientific data, illustrating a study on periodontitis and mortality",{"slug":78,"title":79,"date":80,"modified":8,"excerpt":81,"minutes":10,"image":82,"service":14,"en":83},"importanza-del-monitoraggio-nella-terapia-parodontale","L’importanza del monitoraggio nella terapia parodontale","2021-03-31","La parodontite in Italia è tra le principali cause di perdita dei denti nell’adulto (edentulia). Il suo esordio è dovuto principalmente all’accumulo di placca batterica sulle superfici dentali che…",{"width":12,"height":13,"alt":79},{"slug":84,"title":85,"description":86,"excerpt":87,"minutes":10,"summary":88,"keywords":92,"imageAlt":98},"periodontal-maintenance-reassessment-visits","Why Monitoring Matters in Periodontal Treatment","Periodontitis can be stabilised but not cured. Learn how active treatment and supportive therapy work, and why yearly periodontal reassessment visits matter.","Periodontitis in Italy is one of the leading causes of tooth loss in adults (edentulism). It is mainly triggered by bacterial plaque building up on the tooth surfaces: if this is not removed, in a…",[89,90,91],"Periodontitis is among the leading causes of tooth loss in adults in Italy and is mainly triggered by bacterial plaque building up on the teeth.","Because periodontitis is chronic, treatment is split into active therapy to halt the disease and supportive therapy to prevent relapse.","Supportive therapy includes an essential yearly periodontal reassessment visit, which is separate from regular professional dental cleaning sessions.",[93,94,95,96,97],"periodontal maintenance","supportive periodontal therapy","periodontal reassessment","periodontitis treatment phases","periodontitis relapse","Dentist examining 3D dental scans on a light box",1793907066977]