[{"data":1,"prerenderedAt":102},["ShallowReactive",2],{"notizie-en-precision-dentistry-applications-and-benefits":3},{"post":4,"body":30,"related":31},{"slug":5,"title":6,"date":7,"modified":7,"excerpt":8,"minutes":9,"image":10,"service":13,"en":14},"odontoiatria-di-precisione-campi-di-applicazione-e-vantaggi","Odontoiatria di precisione: campi di applicazione e vantaggi","2021-10-26","La medicina di precisione nasce in ambito oncologico e, grazie alla sua capacità predittiva, ha permesso di salvare vite umane. Oggi viene applicata anche all’odontoiatria grazie ad esami diagnostici…",3,{"width":11,"height":12,"alt":6},1200,628,null,{"slug":15,"title":16,"description":17,"excerpt":18,"minutes":9,"summary":19,"keywords":23,"imageAlt":29},"precision-dentistry-applications-and-benefits","Precision Dentistry: Applications and Benefits","What precision dentistry is and how genetic, molecular and saliva tests may personalise care for early childhood caries, periodontitis and oral cancer.","Precision medicine was born in oncology and, thanks to its predictive power, it has saved lives. Today it is also being applied to dentistry, through diagnostic tests such as genetic and molecular…",[20,21,22],"Precision dentistry uses genetic and molecular tests, including a simple saliva sample, to predict some oral diseases and personalise treatment.","Genetics is currently thought to explain about 40–70% of the onset of early childhood caries, the most common chronic disease of childhood.","Oral cancers account for almost half of all head and neck cancers, and biomarker-based tests allow them to be diagnosed at an early stage.",[24,25,26,27,28],"precision dentistry","genetic testing in dentistry","saliva diagnostics","personalised dental treatment","oral cancer early diagnosis","Close-up of a scientist working with laboratory samples","\u003Cp>\u003Cem>Precision medicine was born in oncology and, thanks to its predictive power, it has saved lives. Today it is also being applied to dentistry, through diagnostic tests such as genetic and molecular testing that, from a simple saliva sample, make it possible to predict the onset of some diseases of the mouth and to apply highly personalised treatments with a predictable chance of success.\u003C\u002Fem>\u003C\u002Fp>\n\u003Cp>Dentistry has always been a “precision” discipline: one patient’s treatment is rarely the same as another’s, since every mouth has unique characteristics. Thanks to recent advances in genomics and artificial intelligence, dental medicine will become ever more precise, and we will see a strong push in the field of prevention. This revolution, however, is only taking its first steps, and it will still be some time before the clinical use of genetic and molecular analysis becomes an everyday reality in dental practices.\u003C\u002Fp>\n\u003Cp>This approach will make it possible to develop highly personalised treatments, based on the patient’s genetic, biological and socio-environmental characteristics, and also to predict the onset of disease, thanks to the use of saliva in diagnostics: analysing it can reveal both dental and systemic conditions. It is a modern, multifaceted, data-driven approach to oral health that uses individual characteristics to stratify similar patients into phenotypic groups.\u003C\u002Fp>\n\u003Cp>One example of its application concerns \u003Cstrong>early childhood caries\u003C\u002Fstrong>, the most common chronic disease of childhood, whose onset is linked both to environmental factors, such as fluoride intake and eating habits, and to individual ones, such as tooth anatomy, enamel quality, saliva composition, the composition of the microbiome and immune defences. Genetics is currently thought to explain around 40–70% of the onset of the disease.\u003C\u002Fp>\n\u003Cp>Genomics will also play an increasingly important role in the prevention and \u003Cstrong>treatment of periodontitis\u003C\u002Fstrong>, a polymicrobial infection (caused by several bacteria) whose clinical variability depends on variations in genetic factors. Some people are, in fact, more predisposed than others to developing this disease.\u003C\u002Fp>\n\u003Cp>Another very important area is \u003Cstrong>oral cancer\u003C\u002Fstrong>. These tumours account for almost half of all cancers affecting the head and neck. Tests based on detecting biomarkers make it possible to diagnose these carcinomas at an early stage and stop them from developing. Once the nature of the tumour has been established, the oncologist or oral pathologist can determine the personalised treatment best suited to the patient’s genetic characteristics, with a greater chance that the treatment will succeed.\u003C\u002Fp>\n\u003Cp>Finally, precision dentistry can also be applied \u003Cstrong>in orthodontics\u003C\u002Fstrong>, since the aetiology of malocclusion depends heavily on genetic as well as environmental causes.\u003C\u002Fp>\n\u003Cp>As we have seen, precision medicine is a paradigm shift that calls for a new way of thinking about diagnostic categories. This approach uses data on patients’ risk factors (including, but not limited to, genetic, environmental and behavioural health factors), rather than expert opinion or clinical presentation alone, to redefine the traditional categories of health and disease. The ultimate goal is to give patients accurate and timely diagnoses and to improve treatment and outcomes, ushering in a new era of medicine in which interventions will be increasingly tailored to each individual patient.\u003C\u002Fp>\n\u003Cp>\u003Cem>Sources:\u003C\u002Fem>\u003Cbr>\n\u003Cstrong>\u003Cem>Precision dentistry in early childhood: the central role of genomics\u003C\u002Fem>\u003C\u002Fstrong>\u003Cbr>\n\u003Cem>Kimon Divaris, DDS, PhD\u003C\u002Fem>\u003Cbr>\n\u003Cstrong>\u003Cem>Odontoiatria di precisione a che punto siamo?\u003C\u002Fem>\u003C\u002Fstrong>\u003Cbr>\n\u003Cem>Dental Journal\u003C\u002Fem>\u003Cbr>\n\u003Cstrong>\u003Cem>Advances in precision oral health\u003C\u002Fem>\u003C\u002Fstrong>\u003Cbr>\n\u003Cem>James D. Beck, Kamaira Philips, Kevin Moss, Kimon Divaris, Thiago Morelli, Steven Offenbacher\u003C\u002Fem>\u003C\u002Fp>\n\u003Cp>\u003Cem>Credits: Photo by Braňo on Unsplash\u003C\u002Fem>\u003C\u002Fp>",[32,56,79],{"slug":33,"title":34,"date":35,"modified":35,"excerpt":36,"minutes":37,"image":38,"service":39,"en":40},"una-bocca-sana-aiuta-anche-il-pianeta","Una bocca sana aiuta anche il pianeta","2022-10-13","Forse non tutti sanno che il settore sanitario ha un impatto notevole sull’ambiente: ben il 5% delle emissioni di gas serra sono dovute all’assistenza sanitaria e, in questo ambito, il settore…",2,{"width":11,"height":12,"alt":34},"igiene-prevenzione",{"slug":41,"title":42,"description":43,"excerpt":44,"minutes":37,"summary":45,"keywords":49,"imageAlt":55},"healthy-mouth-healthy-planet-dentistry-carbon-footprint","A Healthy Mouth Helps the Planet Too","Dentistry has a real carbon footprint, from fillings to nitrous oxide. Find out how prevention and simple daily habits protect both your smile and the planet.","Not everyone knows that the healthcare sector has a significant impact on the environment: as much as 5% of greenhouse gas emissions come from healthcare, and dentistry is a major contributor within…",[46,47,48],"Healthcare causes 5% of greenhouse gas emissions, and dentistry is a major contributor within the sector.","A filling produces about 15 kg of CO2eq, a root canal treatment 23 kg and a denture between 58 and 71 kg.","Prevention through daily brushing with fluoride toothpaste, flossing and professional dental cleaning twice a year is the best way to protect both your mouth and the planet.",[50,51,52,53,54],"dentistry carbon footprint","sustainable dental care","environmental impact of dentistry","nitrous oxide greenhouse gas","eco-friendly oral hygiene","Two bamboo toothbrushes in a glass jar",{"slug":57,"title":58,"date":59,"modified":59,"excerpt":60,"minutes":61,"image":62,"service":13,"en":63},"diagnostica-orale-in-gravidanza-quali-rischi-per-il-nascituro","Diagnostica orale in gravidanza: quali rischi per il nascituro?","2022-09-27","Andare dal dentista durante la gravidanza non solo è sicuro ma, come abbiamo visto, assolutamente necessario per il benessere della mamma e del nascituro in caso di problemi a denti e gengive…",1,{"width":11,"height":12,"alt":58},{"slug":64,"title":65,"description":66,"excerpt":67,"minutes":61,"summary":68,"keywords":72,"imageAlt":78},"dental-x-rays-during-pregnancy-safety","Dental X-Rays During Pregnancy: Are They Safe for Your Baby?","Are dental X-rays safe in pregnancy? A JADA review of studies from 1957 to 2021 found necessary dental radiography safe at any stage with proper equipment.","Going to the dentist during pregnancy is not only safe but, as we have seen, absolutely necessary for the wellbeing of mother and baby if there are problems with the teeth or gums. Unfortunately…",[69,70,71],"Recent data show that fewer than half of pregnant women have dental check-ups, mainly because they worry about anaesthesia and dental X-rays.","A JADA review of findings from 1957 to 2021 concluded that necessary dental radiography is safe at any stage of pregnancy if adequate safety equipment is used.","When performed correctly, dental X-rays produce so little ionising radiation that they are unlikely to cause anomalies or malformations in the embryo or foetus.",[73,74,75,76,77],"dental X-rays during pregnancy","is it safe to go to the dentist when pregnant","pregnancy and oral health","dental radiography safety","dental care in pregnancy","Pregnant woman holding her belly",{"slug":80,"title":81,"date":82,"modified":82,"excerpt":83,"minutes":37,"image":84,"service":85,"en":86},"via-il-dente-via-il-ricordo-la-cattiva-salute-orale-puo-compromettere-la-tua-memoria","Via il dente, via il ricordo: la cattiva salute orale può compromettere la tua memoria","2022-09-08","Se vuoi proteggere il tuo cervello non trascurare l’igiene orale: ogni dente perso, infatti, può causare un aumento del’1,4% del rischio di un deterioramento cognitivo e dell’1,1% di sviluppare…",{"width":11,"height":12,"alt":81},"parodontologia",{"slug":87,"title":88,"description":89,"excerpt":90,"minutes":37,"summary":91,"keywords":95,"imageAlt":101},"tooth-loss-memory-and-dementia-risk","Tooth Loss, Memory and Dementia: How Oral Health Affects the Brain","Each lost tooth raises the risk of cognitive impairment by 1.4% and dementia by 1.1%, a JAMDA meta-analysis found. Learn how oral health protects memory.","If you want to protect your brain, do not neglect your oral hygiene: each tooth you lose can increase the risk of cognitive impairment by 1.4% and the risk of developing some form of dementia by 1.1%.",[92,93,94],"A JAMDA meta-analysis found that each lost tooth increases the risk of cognitive impairment by 1.4% and the risk of developing dementia by 1.1%.","Adults who had lost more than one tooth were 1.5 times more likely to develop cognitive impairment and 1.3 times more likely to develop dementia.","The risk dropped sharply when missing teeth were replaced with prostheses or dentures, possibly because tooth loss makes chewing difficult and leads to nutritional deficiencies.",[96,97,98,99,100],"tooth loss and dementia","oral health and memory","missing teeth cognitive decline","gum disease and alzheimer’s","dentures and dementia risk","Older adult smiling, illustrating oral health and memory",1793907065894]